HormonesSeptember 25, 2026

Types of Hormone Therapy: What Gets Tested and Prescribed

Gabriel Rocha, PA-C, MMSc, IFMCP
Gabriel Rocha, PA-C, MMSc, IFMCP

IFM Certified Practitioner · Yale MMSc · Updated September 25, 2026

Types of Hormone Therapy: What Gets Tested and Prescribed - Med Matrix functional medicine blog

Hormone therapy means giving the body a hormone it is not making enough of, or helping it make more of its own. That is broader than most people expect. Thyroid medication is hormone therapy. So is hormone replacement therapy, or HRT, which is prescribed for women whose estrogen and progesterone have dropped. So is testosterone replacement therapy, or TRT, prescribed for men whose testosterone has fallen below where it should be.

People usually arrive at this subject through one of those doors and assume it is the whole house. It is not, and that matters, because the door you come in through tends to decide what gets tested. Somebody who arrives convinced they need HRT can end up with a thyroid answer. Somebody sure their testosterone is the problem can turn out to have a sleep problem driving it.

This page is an index to the whole category: what gets measured, what the measurements are for, and where to read the detail on each branch.

Start with what gets measured

Hormones are a system that talks to itself. Cortisol influences thyroid conversion. Thyroid influences how you use energy. Blood sugar influences everything. Measuring one hormone in isolation and treating what you find is how people end up on a prescription that does not fix what they came in for.

A hormone workup worth the name covers several things at once rather than a single number. That is the reason our own process runs an 80+ biomarker test and a full body scan before anybody discusses a prescription, and why the results appointment is a full hour rather than a five-minute readout.

Two articles are worth reading before any blood draw. Why won't my doctor test my hormones explains why a standard visit often declines to look, and what belongs on the panel before starting HRT covers what a complete workup includes for women.

Thyroid, which is where a lot of hormone stories actually start

Thyroid is the branch people skip, and it is frequently the one that explains the symptoms. It is also the clearest example of why hormone therapy is not the same thing as replacement therapy for sex hormones.

The common failure is a normal TSH reading treated as a closed case. Why a normal TSH does not rule out a thyroid problem is the article to read if you have been told your thyroid is fine and you do not feel fine. The link between thyroid issues and unexplained weight gain and thyroid belly shape deal with the presentation people most often notice first, and recognizing and treating thyroid imbalance covers the functional medicine approach to it.

Hormone therapy for women

Med Matrix is an HRT clinic offering hormone replacement therapy for women. The questions that come up most are whether to start, what form to take it in, and what the risks actually are now that the evidence has moved.

On the decision itself, the pros and cons of HRT and the questions every woman should ask before starting are the two to read first. The signs that point toward needing it covers what usually prompts the conversation.

On the stage before that, am I in perimenopause and what those two words actually mean are the ones people search for at two in the morning. The symptoms women miss in their 30s and 40s is the fuller list.

On form and delivery, bioidentical hormones explains what the term does and does not mean, and hormone pellets covers what you give up by choosing them. If you have hit a supply problem, what to do if you cannot fill an estrogen patch is practical.

On risk, the FDA dropping the boxed warning is the most significant change in this area in years, and HRT versus natural menopause remedies compares the options on evidence. Menopause and autoimmune disease covers why flares can hit harder during the transition.

Fertility sits adjacent to all of it. The thyroid, prolactin and progesterone tests to run first is the starting point there. The fuller picture is on our hormone replacement therapy page and in women's health optimization in Maine.

Hormone therapy for men

Med Matrix is a TRT clinic offering testosterone replacement therapy for men. The pattern here is different: most men arrive having already decided testosterone is the issue, and the useful work is often confirming whether that is true.

Start with the signs most men miss and the symptoms ignored for years. Low libido in men is worth reading precisely because it covers causes beyond low testosterone, which is the part that gets skipped.

On treatment itself, what to expect at a first visit, results at week 2, 4, 8 and 12, and a TRT dosage guide. Does TRT work without lifestyle changes answers the question most men would rather not ask.

On safety and side effects, what the TRAVERSE trial found, whether TRT causes hair loss, and testosterone cypionate side effects. On cost, a TRT pricing breakdown.

Two adjacent ones: foods that boost testosterone for the lifestyle side, and men's health optimization for how testosterone, thyroid and labs fit together. The service page is testosterone replacement therapy.

Growth hormone peptides, which are adjacent but not the same

Sermorelin and similar compounds signal the pituitary rather than replacing a hormone directly, which puts them in a different category from the therapies above. What sermorelin is and how it works covers the mechanism, and our peptide reference list places it among the other peptides and their regulatory status.

Choosing where to go

If you are comparing clinics, how to find a hormone therapist who actually knows hormones and what to expect at a hormone clinic in Maine are the two practical ones. What hormone therapy costs without insurance covers the money question directly.

Frequently asked questions

What is hormone therapy?

Giving the body a hormone it is not producing enough of, or prompting it to produce more of its own. It covers thyroid medication, hormone replacement therapy for women, testosterone replacement therapy for men, and several smaller categories.

Is hormone therapy the same as HRT?

No. HRT is one branch of it. Hormone replacement therapy specifically refers to replacing estrogen and progesterone in women. Thyroid treatment is also hormone therapy and has nothing to do with HRT.

What is the difference between HRT and TRT?

Different hormones and different patients. Hormone replacement therapy replaces estrogen and progesterone in women. Testosterone replacement therapy replaces testosterone in men. They are separate treatments with separate evidence bases.

What tests do I need before starting hormone therapy?

More than one hormone. Because thyroid, cortisol, blood sugar and sex hormones influence each other, a panel that looks at a single number can point in the wrong direction. What belongs on the panel goes through it.

Can hormone therapy be stopped?

That is a decision made with your prescribing provider, and it depends on what you are taking it for and what your labs show. It is not a decision to make from an article.

Where to start

If you have read three of these and still are not sure which branch applies to you, that is the normal experience, and it is what testing is for. Start Feeling Like Yourself Again with a panel that looks at the whole system rather than the one hormone you came in asking about.

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