Semaglutide Weight Loss
Semaglutide Weight Loss in Maine and New Hampshire
GLP-1 therapy works best when it targets the root cause, not just the symptom. Med Matrix combines semaglutide with an 80-biomarker panel to identify what is driving your weight gain and build a protocol designed to deliver results that last.
What Is Semaglutide and How Does It Work?
Semaglutide is a GLP-1 receptor agonist that mimics a hormone produced in the gut after eating. It slows gastric emptying, reduces appetite signals in the brain, and improves insulin sensitivity. Clinical trials show average weight loss of 15 to 17 percent of body weight over 68 weeks. At Med Matrix, semaglutide is prescribed as part of a comprehensive medical weight loss program. Every patient receives an 80+ biomarker lab panel before starting to check for thyroid dysfunction, insulin resistance, and hormone imbalances that could be contributing to weight gain independently. An InBody 770 body composition scan tracks fat loss versus muscle loss at every visit.
What's Included in the Med Matrix Semaglutide Program
Semaglutide here is a full medical weight loss program, not a subscription for injections. Here is what your program covers.
80+ Biomarker Baseline Panel
Full thyroid, fasting insulin, HbA1c, hormones, and inflammation markers measured before prescribing, so root causes of weight gain get treated too.
InBody 770 Body Composition Scan
Fat mass and muscle mass tracked separately at every visit, so you can confirm you are losing fat and keeping muscle, not just watching the scale.
One-Hour Provider Consultation
A full hour walking through every result, followed by a personalized protocol built around your labs, metabolism, and weight loss goals.
Gradual Dose Titration
Weekly semaglutide injections started low and increased gradually to minimize nausea and digestive side effects while appetite control builds.
Muscle Protection Built In
Protein targets, strength training guidance, and hormone support where labs call for it, so rapid weight loss does not cost you muscle.
Direct Care Team Access
Questions between visits go to your care team, not a call center. Dose adjustments happen when your body needs them.
Full onboarding runs approximately $1,200 to $1,500 all-in. Semaglutide medication costs vary by protocol. New patients receive a $100 voucher toward their first visit. HSA and FSA accepted.
LOCATIONS WE SERVE
Find Semaglutide Near You
Greater Portland & Surrounding Suburbs
Casco Bay & Coastal Communities
Sebago Lake & Western Lakes Region
Southern Maine Coast
New Hampshire
Who Leads Weight Loss Care at Med Matrix
These providers build and monitor every weight loss protocol personally.
Real Weight Loss Patient Stories
Hear from patients who lost weight with Med Matrix.

Lindsay
Lindsay gained 43 pounds in about 6 months while her PCP kept telling her labs were fine. Two close family members recommended functional medicine, and after researching online she connected with Med Matrix. Working with Colin, she discovered her A1C was raised and her cholesterol and triglycerides were past 300, all against a severe cardiac family history her PCP had never taken seriously. She has since lost weight, stopped a 3-year sleep medication, sleeps through the night, and describes the experience as "life-changing."
“I want to want to get out of bed.”

Gordon
Gordon, who turned 65 and weighed 285 lbs, came to Med Matrix after 40 years with a conventional doctor who never resolved his migraines, fatigue, or chronic conditions. Over roughly a year, he lost 50 lbs, came off three prescription medications, and resolved his high blood pressure, high cholesterol, knee pain, and arthritis through a combination of Dr. Rose's guidance, dietary changes, and supplements.
“Life-changing. It's just incredible how seeing a doctor who cares and medicine that works.”
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FAQ
Semaglutide Questions
Common questions about semaglutide weight loss at Med Matrix.
Semaglutide is a GLP-1 receptor agonist that reduces appetite, slows gastric emptying, and improves insulin signaling. Originally developed for type 2 diabetes, it has become one of the most clinically studied tools for sustained weight loss. At Med Matrix, semaglutide is prescribed as part of a broader protocol that includes lab work and lifestyle support, not as a standalone medication.
Before prescribing semaglutide, we run an 80-biomarker blood panel to identify what is driving your weight gain. Thyroid dysfunction, insulin resistance, hormonal imbalances, and chronic inflammation all contribute to stubborn weight. We address those root causes alongside the GLP-1 therapy so that results hold long term, not just while you are on the medication.
Full onboarding runs approximately $1,200 to $1,500 all-in, covering your 80-biomarker lab panel, InBody 770 body composition scan, provider prep time, and a full one-hour provider consultation. Semaglutide medication costs vary depending on your protocol. New patients receive a $100 voucher toward their first visit. We accept HSA and FSA accounts.
The most common side effects are nausea, mild digestive discomfort, and reduced appetite, especially in the first few weeks as your dose increases. Most patients tolerate the medication well when titrated gradually. Your provider monitors your labs and adjusts your protocol as needed throughout your program.
Semaglutide is appropriate for adults who have struggled to lose weight through diet and exercise alone, particularly those with insulin resistance, metabolic syndrome, or a BMI over 27 with a related health condition. During your first visit, your provider reviews your full lab panel and health history to determine whether semaglutide fits your goals and your biology.
Both are GLP-1 receptor agonists that reduce appetite and support weight loss. Tirzepatide also targets a second receptor (GIP), which may produce slightly greater weight loss in some patients. At Med Matrix, your provider reviews your full lab panel, metabolic markers, and health history to determine which medication fits your biology. The right choice depends on your individual results, not a generic recommendation.
Most patients notice reduced appetite and less food noise within the first two to four weeks. Measurable weight loss typically begins within the first month, with steady progress over three to six months as your dose is gradually increased. Your provider tracks your body composition with InBody scans at each visit, so you can see changes in fat mass and muscle mass separately, not just the number on the scale.
Yes. Semaglutide is FDA-approved for weight management in adults without diabetes. At Med Matrix, we prescribe it for patients with a BMI over 27 who have a weight-related health condition, or a BMI over 30. Your provider confirms eligibility based on your lab results and health history during your first visit.

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