The Med Matrix Podcast

A free functional medicine podcast from the provider team at Med Matrix in South Portland, Maine. Each episode takes the same explanations our providers give patients during 60-minute consultations and puts them on camera for anyone to watch.

Episodes cover the questions patients actually bring in: how hormones shift through perimenopause and menopause, why gut health sits behind so many stubborn symptoms, what a full thyroid panel catches that TSH alone misses, and how to read your own lab results. Most episodes run 40 to 80 minutes, and every episode page includes a written summary, key topics, FAQs, and the full video.

Every host is a licensed clinical provider who sees patients each week, and there are no supplement sponsorships or mid-episode sales pitches. Browse the episodes below, and if a topic sounds like what you are living with, you can start with a free discovery call.

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Health Trends Worth Paying Attention To: Peptides, Hormones, and More - Med Matrix Podcast
47:45
Functional Medicine

Health Trends Worth Paying Attention To: Peptides, Hormones, and More

with Brian (marketing, host) & Colin Renaud, PA-C

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The Testosterone Crisis: What to Do About Low T - Med Matrix Podcast
68:00
Testosterone

The Testosterone Crisis: What to Do About Low T

with Cole Siefer (co-founder, host) & Colin Renaud, PA-C

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Peptides Over 40: What They Are and How to Use Them Safely - Med Matrix Podcast
62:39
Peptides

Peptides Over 40: What They Are and How to Use Them Safely

with Leah (marketing director, host) & Colin Renaud, PA-C

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Hormone Replacement Therapy Explained: Benefits, History, and Root Causes - Med Matrix Podcast
35:18
Hormones

Hormone Replacement Therapy Explained: Benefits, History, and Root Causes

with Cole Siefer (co-founder, host) & Sophia, nurse practitioner

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GLP-1s Explained: Benefits, Risks, and the Weight Loss Buzz - Med Matrix Podcast
63:04
GLP-1 & Weight Loss

GLP-1s Explained: Benefits, Risks, and the Weight Loss Buzz

with Dr. Sasha Rose & Colin Renaud, PA-C

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What Insulin Resistance Means (Beyond Just Diabetes) - Med Matrix Podcast
52:48
Metabolic Health

What Insulin Resistance Means (Beyond Just Diabetes)

with Dr. Sasha Rose & Brian Leggott (co-owner)

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Preventing the Early Signs of Cognitive Decline - Med Matrix Podcast
59:18
Brain Health

Preventing the Early Signs of Cognitive Decline

with Cole Siefer (co-founder, host) & Colin Renaud, PA-C

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Natural Brain Support for ADHD in Adults - Med Matrix Podcast
58:13
Brain Health

Natural Brain Support for ADHD in Adults

with Colin Renaud, PA-C & Dr. Sasha Rose

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Normal vs Healthy: Why Your Labs Look Fine but You Feel Awful - Med Matrix Podcast
40:27
Functional Medicine

Normal vs Healthy: Why Your Labs Look Fine but You Feel Awful

with Leah (media marketing director, host) & Dr. Sasha Rose

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Metabolic Damage and How to Work on Repair - Med Matrix Podcast
53:31
Metabolic Health

Metabolic Damage and How to Work on Repair

with Cole Siefer (co-founder, host) & Dr. Sasha Rose

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Prevention vs Profit: How Health Insurance Shapes the Care You Get - Med Matrix Podcast
59:55
Healthcare System

Prevention vs Profit: How Health Insurance Shapes the Care You Get

with Cole Siefer (co-founder, host) & Dr. Sasha Rose

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How to Optimize Your Thyroid and Have More Energy - Med Matrix Podcast
56:13
Thyroid

How to Optimize Your Thyroid and Have More Energy

with Cole Siefer (co-founder, host) & Dr. Sasha Rose

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The Menopausal Toll on the Body with Dr. Sasha Rose - Med Matrix Podcast
70:51
Women's Health

The Menopausal Toll on the Body with Dr. Sasha Rose

with Cole Siefer (co-founder, host) & Dr. Sasha Rose

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Decoding Your Normal Labs: Why Normal Is Not the Same as Optimal - Med Matrix Podcast
50:27
Lab Testing

Decoding Your Normal Labs: Why Normal Is Not the Same as Optimal

with Cole Siefer (co-founder, host) & Dr. Sasha Rose

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Why Your Bone Density Keeps Dropping: PPIs, Vitamin D Myths, and What Actually Works - Med Matrix Podcast
5:37
Bone Health

Why Your Bone Density Keeps Dropping: PPIs, Vitamin D Myths, and What Actually Works

with Cole Siefer (interviewer) & Dr. Sasha Rose (provider)

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Why Bisphosphonates and PPIs Together Increase Fracture Risk by 52% (and What Works for Bone Health) - Med Matrix Podcast
49:09
Bone Health

Why Bisphosphonates and PPIs Together Increase Fracture Risk by 52% (and What Works for Bone Health)

with Cole Siefer (host/interviewer) & Dr. Sasha Rose (provider)

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Osteoporosis Prevention: Bone Health, Hormones, and What Conventional Medicine Misses - Med Matrix Podcast
49:50
Bone Health

Osteoporosis Prevention: Bone Health, Hormones, and What Conventional Medicine Misses

with Cole Siefer (co-founder, host) & Dr. Sasha Rose

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Why You Keep Waking Up at 3AM: Cortisol Dysregulation, the HPA Axis, and How to Fix It - Med Matrix Podcast
57:58
Sleep

Why You Keep Waking Up at 3AM: Cortisol Dysregulation, the HPA Axis, and How to Fix It

with Cole Siefer (host/interviewer) & Dr. Sasha Rose (naturopathic doctor, lead provider at Med Matrix)

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PMS, Acne, and Stubborn Belly Fat? How Your Gut Microbiome Controls Estrogen Levels - Med Matrix Podcast
41:50
Women's Health

PMS, Acne, and Stubborn Belly Fat? How Your Gut Microbiome Controls Estrogen Levels

with Cole Siefer (host/moderator) & Dr. Rose (naturopathic doctor, licensed acupuncturist)

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The HPA Axis: Cortisol, Stress, and Adrenal Health with Dr. Rose - Med Matrix Podcast
58:22
Hormones

The HPA Axis: Cortisol, Stress, and Adrenal Health with Dr. Rose

with Cole Siefer (co-founder, host) & Dr. Sasha Rose

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The Estrobolome: How Gut Health Shapes Estrogen and Mood in Women - Med Matrix Podcast
41:55
Women's Health

The Estrobolome: How Gut Health Shapes Estrogen and Mood in Women

with Cole Siefer (co-founder, host) & Dr. Sasha Rose

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Why Your Total Testosterone Is Misleading: SHBG, DHEA, and the Estrobolome Explained - Med Matrix Podcast
36:36
Hormones

Why Your Total Testosterone Is Misleading: SHBG, DHEA, and the Estrobolome Explained

with Cole Siefer & Dr. Sasha Rose

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Are You Vitamin D Deficient? Why Your Doctor Says 23 Is Normal but Functional Medicine Targets 60-80 - Med Matrix Podcast
38:27
Vitamins

Are You Vitamin D Deficient? Why Your Doctor Says 23 Is Normal but Functional Medicine Targets 60-80

with Cole Siefer (co-founder, host) & Dr. Rose (provider at Med Matrix)

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Vitamin and Hormone Deficiencies with Dr. Sasha Rose - Med Matrix Podcast
76:06
Vitamins

Vitamin and Hormone Deficiencies with Dr. Sasha Rose

with Cole Siefer (co-founder, host) & Dr. Sasha Rose

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IBS, SIBO, and Leaky Gut: What Your Gastroenterologist Is Not Testing For - Med Matrix Podcast
28:11
Gut Health

IBS, SIBO, and Leaky Gut: What Your Gastroenterologist Is Not Testing For

with Cole Siefer & Dr. Sasha Rose

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Everything Thyroid and Reversing Type 2 Diabetes with Dr. Sasha Rose - Med Matrix Podcast
58:34
Thyroid

Everything Thyroid and Reversing Type 2 Diabetes with Dr. Sasha Rose

with Cole Siefer (co-founder, host) & Dr. Sasha Rose

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SIBO and Menopause: A Functional Medicine Approach with Dr. Sasha Rose - Med Matrix Podcast
78:46
Women's Health

SIBO and Menopause: A Functional Medicine Approach with Dr. Sasha Rose

with Cole Siefer (co-founder, host) & Dr. Sasha Rose

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Gut Health and Probiotics: What Actually Works - Med Matrix Podcast
56:02
Gut Health

Gut Health and Probiotics: What Actually Works

with Cole Siefer (co-founder, host) & Dr. Sasha Rose

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Bioidentical HRT for Women Over 40: Testosterone, the Dutch Test, and Why Mail-Order Hormones Fall Short - Med Matrix Podcast
33:27
HRT for Women

Bioidentical HRT for Women Over 40: Testosterone, the Dutch Test, and Why Mail-Order Hormones Fall Short

with Cole Siefer (co-founder, host) & Dr. Rose (naturopathic physician, acupuncturist)

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Menopause and Bioidentical Hormone Replacement Therapy - Med Matrix Podcast
61:58
HRT for Women

Menopause and Bioidentical Hormone Replacement Therapy

with Cole Siefer (co-founder, host) & Dr. Sasha Rose

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Mycotoxin Exposure Symptoms: How Hidden Mold Causes Brain Fog, Fatigue, and Chronic Illness - Med Matrix Podcast
28:36
Mold & Toxins

Mycotoxin Exposure Symptoms: How Hidden Mold Causes Brain Fog, Fatigue, and Chronic Illness

with Cole Siefer & Dr. Sasha Rose

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Do You Actually Have Parasites? How to Tell, How to Test, and Why DIY Cleanses Backfire - Med Matrix Podcast
26:38
Gut Health

Do You Actually Have Parasites? How to Tell, How to Test, and Why DIY Cleanses Backfire

with Cole Siefer & Dr. Sasha Rose

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Healthspan vs. Lifespan: How Exercise, Fiber, and GLP-1 Slow Cellular Aging (Dr. Kreher) - Med Matrix Podcast
23:43
Functional Medicine

Healthspan vs. Lifespan: How Exercise, Fiber, and GLP-1 Slow Cellular Aging (Dr. Kreher)

with Dr. Kreher (presenter, sports and functional medicine physician at Med Matrix)

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Stem Cells, PRP, and Peptides for Joint Pain: What Actually Works in Regenerative Medicine - Med Matrix Podcast
34:36
Stem Cells & Peptides

Stem Cells, PRP, and Peptides for Joint Pain: What Actually Works in Regenerative Medicine

with Dr. Jeff Kreher (solo presentation, no interviewer) & board-certified Internal Medicine & board-certified Pediatrics & Primary Care Sports Medicine & IFM-certified functional medicine provider at Med Matrix

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