Med Matrix functional medicine and wellness clinic

Muscle Loss Treatment

Losing muscle isn't inevitable. It's a signal that something hormonal, metabolic, or nutritional is off. We test testosterone, growth hormone markers, thyroid function, and inflammatory markers to find why you're losing muscle and build a protocol to reverse it.

4.9 stars150+ reviews3,000+ patients7 providers
Muscle Loss Treatment - functional medicine at Med Matrix South Portland Maine

Why You're Losing Muscle Despite Working Out

You're training consistently. You're eating enough protein (or you think you are). But you're getting weaker, losing definition, and watching muscle disappear while fat accumulates. Your doctor says it's normal aging. It isn't.

Muscle loss (sarcopenia) accelerates when hormones decline. Testosterone is the primary anabolic hormone in both men and women. When it drops, muscle protein synthesis slows down regardless of how hard you train. Growth hormone declines. Thyroid function slows metabolism. Cortisol from chronic stress actively breaks down muscle tissue. Inflammation from gut dysfunction or poor metabolic health creates a catabolic environment where muscle can't be maintained.

The standard response from conventional medicine is "lift weights and eat more protein." That's good advice, but it doesn't work when the hormonal and metabolic environment won't support muscle growth. You can't out-train bad hormones.

A man in his early 40s comes in with a testosterone of 320. His conventional doctor says, 'You're totally fine.' But he's not, though. That's the thing.

Colin Renaud, PA-C on Why Testosterone Gets Missed

Provider Insight

My old level was really probably closer to my baseline. And if you take that and cut it in half, even though my half was still in what medical professionals say is an acceptable range, that's not necessarily what's acceptable for my body.

Ryan: Why 'Normal Range' Wasn't Normal for Him

Patient Story

My old level was really probably closer to my baseline. And if you take that and cut it in half, even though my half was still in what medical professionals say is an acceptable range, that's not necessarily what's acceptable for my body.

Ryan: Why 'Normal Range' Wasn't Normal for Him

Patient Story

I wake up and not feel that, you're like, 'Wow.' My quality of life is completely different.

Caleb: Quality of Life Completely Changed

Patient Story

Peptides are for people that are doing proactive health. You can't just take a peptide and it's going to answer all your prayers and do your bad diet and sit on the couch all the time.

Colin Renaud, PA-C: Peptides Need a Foundation to Work

Provider Insight

I ran over 6 miles, no pain at all.

Eric: BPC-157 Resolved Chronic Knee Pain in One Month

Patient Story

Personalized health care is really what promotes longevity. Unfortunately, that's what the mainstream medical community doesn't take into account either.

Colin Renaud, DC, PA-C: Personalized Health Care Promotes Longevity

Provider Insight

Life-changing. It's just incredible how seeing a doctor who cares and medicine that works.

Gordon: Life-Changing Results at 65

Patient Story

Everything Under One Roof

Advanced testing, personalized protocols, and real results from a team that treats the whole picture.

Med Matrix clinic building in South Portland, Maine

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How We Reverse Muscle Loss

We start with the full picture: testosterone (total and free), estrogen, IGF-1 (growth hormone marker), thyroid panel, cortisol, inflammatory markers, insulin resistance markers, and nutrient status. Then we build a protocol based on what's actually deficient.

  • Testosterone optimization. TRT when indicated, or alternatives like enclomiphene for younger men who want to preserve fertility. Testosterone is the foundation of muscle maintenance.
  • Peptide therapy. Growth hormone secretagogues like CJC-1295/Ipamorelin to support lean mass and recovery. BPC-157 for tendon and tissue repair.
  • Thyroid optimization. Subclinical hypothyroidism slows metabolism and impairs recovery. We optimize, not just normalize.
  • Inflammation reduction. Chronic inflammation is catabolic. We identify the source (gut, metabolic, hormonal) and address it.
  • Metabolic support. Insulin sensitivity, nutrient absorption, and protein utilization. Making sure your body can actually use what you're putting into it.

Patients typically see measurable changes in body composition within 8-12 weeks. We track progress with InBody 770 body composition scans at each visit.

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Muscle Loss Treatment FAQ

Not necessarily. We test first and only recommend TRT when labs confirm deficiency. Some patients respond to lifestyle optimization, peptides, or nutrient repletion alone. The protocol depends entirely on your results.

Absolutely. Women lose muscle at an accelerated rate after perimenopause as testosterone and growth hormone decline. Hormone optimization makes a significant difference in maintaining lean mass.

InBody 770 body composition scans measure skeletal muscle mass, body fat percentage, and segmental lean mass. We scan at baseline and at follow-up visits to objectively track changes.

Free practice guide and $100 voucher for functional medicine consultation at Med Matrix

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