PCOS Is Now PMOS: What the New Name Means for Women
Episode Summary
PCOS has a new name. It is now PMOS, polyendocrine metabolic ovarian syndrome, and Dr. Sasha Rose, ND joins host Leah to explain why that is more than a rebrand. The Endocrine Society describes PMOS as a new name for the condition and says it affects 1 in 8 women, more than 170 million worldwide. For years a diagnosis hinged on finding cysts on an ultrasound, so women without them were often told they were fine. The new name puts multiple hormone systems and metabolism in the title, and that changes what gets tested and what gets treated. Dr. Rose covers the symptoms worth watching (irregular or skipped cycles, acne, hair thinning, sugar cravings, fatigue, brain fog), why she wants insulin resistance tested, what birth control does and does not fix, and where GLP-1 medications fit into a plan.
Key Topics
- 1
PCOS to PMOS name change
- 2
Polyendocrine metabolic ovarian syndrome
- 3
Insulin resistance
- 4
Androgen excess
- 5
Why two women with PMOS look different
- 6
The limits of birth control
- 7
GLP-1 medications and metabolism
- 8
Root cause lab testing
Quotable Moments
“if a woman is hearing the term PMOS for the first time, I would like her to take this away, which is that it's not just a rebrand. It's a more accurate, more descriptive name for a condition that has always been about more than the ovaries.”
“it's a whole body condition and ovarian function still matters. So ovulation, menstrual cycles, fertility, the androgen related ovarian activity, it's still part of the condition. It's just not the whole condition.”
“it will shape what actually gets tested and therefore what gets treated. So if it the name is really centered around ovaries then often times those metabolic those endocrine drivers those tests are going to be missed and omitted.”
“Change is slow. Um so I would argue that conventional care is often not always but often probably still treating PMOS as if it's PCOS.”
“it can affect and does affect women differently. You don't have to check every single box. It's going to present differently.”
Treatments Mentioned
FAQ
Women's Health FAQ
The old name pointed straight at the ovaries, so cysts became the thing everyone looked for. Dr. Sasha Rose, ND says PMOS, polyendocrine metabolic ovarian syndrome, is a more accurate description because it names multiple hormone systems and metabolism alongside ovarian function. She is glad the word ovarian stayed in, since ovulation, cycles, fertility and androgen activity are all still part of the condition. They just are not the whole condition.
Polyendocrine means more than one hormone system is involved. Metabolic covers blood sugar, insulin resistance, cravings, energy, inflammation, body composition and long-term metabolic health. Ovarian covers cycles, ovulation and fertility. Dr. Rose says putting metabolic in the title makes it clear that all of that matters, not only what an ultrasound shows.
Dr. Rose lists irregular or skipped periods, acne, facial hair, thinning hair on the scalp, intense sugar cravings, trouble losing weight even when lifestyle choices are good, fatigue and energy crashes, brain fog, mood swings, poor sleep, difficulty conceiving, bloating and inflammation. She adds an honest caveat. Plenty of those symptoms belong to other conditions too, so having three of them does not mean you have PMOS. It is the size of the pattern that makes it worth testing for.
It helps with some of it. Dr. Rose says birth control often manages irregular bleeding, and depending on the type it can help acne. What it usually does not address is insulin resistance, inflammation, gut health, nutrient deficiencies, sleep, stress or the metabolic dysfunction underneath. It works on the cycle and sex hormone side of the condition, which is only one part of it.
Dr. Rose sees GLP-1 medications as one piece of a plan rather than a magic ticket. Separate from weight, she points to improvement in insulin resistance, blood sugar, cravings (the food noise patients describe), visceral fat, non-alcoholic fatty liver disease and inflammation, often without high doses. They are not right for every patient or every case. Since metabolism is now in the name of the condition, she thinks it makes sense to use one of the better metabolic tools available.
Dr. Rose starts with a full health history: your cycles, whether you are on birth control or have an IUD, which symptoms you have now, how long you have had them, and which ones have come and gone. She then reviews how you eat and what you are actually absorbing, your medications and supplements, sleep and stress, metabolic markers, fertility goals when they apply, and labs. That first meeting ends with a personalized plan. At follow-ups she rechecks insulin, androgens, estrogen, progesterone, cortisol and inflammatory markers, and uses the InBody body composition scan so body composition is measured rather than guessed.
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